I had to layer vinyl today and I've had issues in the past, while lining up the registration marks, getting too close to and the marks sticking together and lifting off the backing paper, before I ever got a chance to line them up properly.
I don't know if anyone else does this, but today I put a dab of dish soap on my finger and coated the bottom layer registration marks with a thin coat of soap and was able to slide it around and had no problems with them sticking together, and when I squeegeed them they adhered to each other just fine. Just a tip that worked for me. Hope it helps someone.