I may be way off base here, but at this point I'd be willing to try anything. Win10 does automatic updates and after it updates, other software will update to match it. During these updates there are two issues. The first is that they can really drag down the computer's speed and that could be messing with your file transfer. The second is that the updates may turn certain underlying programs off and back on to implement the update. If any of these affect your USB port then data stops transmitting.
I really get in to outside Christmas lights and most of the controls are run via USB. If Windows updates during a light show there is a high probability that the data flow will be interrupted. Just turning off wifi doesn't do the trick because Windows starts throwing up warnings wanting to update and those can slow or stall data flow. Run wub.exe, a free download, on WIN10 computers to prevent the automatic downloads. It can't hurt to try. I'd disconnect anything else USB also: external harddrives, speakers, printers. Anything that could be stealing time from the USB drivers.