Create your own registration marks in anything you make, add little circles or squares, make sure they are outside the full picture, and that you make them a different color than anything in the Picture.
Then when you go to cut, select your first color in the left color panel then hold down the ctrl key while selecting the color of your registration marks, you can do this with each color, and it will cut the registration marks in each color making it easy to line up. Using clear transfer tape helps also.
Hope this helps.
Allen