Hi CCM I am also on a mac and am looking at buying a MH721.
I am wondering if you found a way to get this running with your mac? Would appreciate any help you can share. I haven't got any of the software yet. I am hoping to set up jobs to be cut from illustrator with a plug in?
Unfortunately some of the comments posted his this thread were misleading... i.e when someone said you need to buy a 'special adapter' - a 'windows machine', they were in fact saying buy a PC to run the MH721 instead of using your mac. This is obviously not what you were hoping to do.